PRF is a concentrated mix of platelets and fibrin, with minimal manipulation or additives, obtained through centrifugation of the patient's blood without anticoagulants. It contains:
Platelets: Rich in growth factors (like PDGF, TGF-β, VEGF) that aid healing.
Fibrin matrix: A natural scaffold that traps cells and releases growth factors gradually.
Leukocytes (white blood cells): Contribute to antimicrobial and healing properties.
